Real-time cardiorespiratory motion management during MRI-guided radiotherapy

Stereotactic radioablation is a novel, non-invasive treatment option for cardiac arrhythmias. The heart is dose sensitive and its motion contributes significantly to dose delivery uncertainties.

To increase dose conformality and minimize toxicity, we explore the parallel application of respiratory MLC-tracking and cardiac-gated radiation delivery for cardiorespiratory motion mitigation for the first time, using the Modus QA QUASAR MRI4D. Cardiac and respiratory motion management decreases dose uncertainties significantly and might therefore be highly beneficial for treating cardiac arrhythmia patients in the future.

Osman Akdag is a PhD candidate at the University Medical Center Utrecht (UMCU) in the Netherlands under supervision of Dr Martin Fast. He obtained his master’s degree in medical engineering at the University of Technology Eindhoven in 2019. During his master’s, Osman worked on diffusion-weighted cardiac MRI in a four-months internship at the King’s College Cardiac MRI group. He has written his master’s thesis on abdominal 4D-MRI at the UMCU. In his current research, Osman is focused on prototyping MRI-guided cardiac radioablation workflows on a hybrid MRI and radiotherapy treatment device. His research is published in renowned, peer-reviewed international journals. He also presented cardiac MRI and dosimetry-focused work at recent AAPM, ISMRM and ESTRO meetings.

The post Real-time cardiorespiratory motion management during MRI-guided radiotherapy appeared first on Physics World.

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